Research

Publications (Google Scholar) 

*: co-1st author, +: co-corresponding author

• Minki P. Lee*, Dae Wook Kim*,+, Ruby Kim, Yu Fang, Amy Bohnert, Srijan Sen, and Daniel B. Forger+, The real-world association between digital markers of circadian disruption and mental health risks, npj Digital Medicine (2024). (link) (Media) 

• Caleb Mayer*, Dae Wook Kim*, Meina Zhang, Minki P. Lee, Daniel B. Forger, Helen J. Burgess, and Chooza Moon+, Predicting circadian phase in community-dwelling later-life adults using actigraphy data, J. Sleep Res. (2024). (link)

• Minki P. Lee*, Dae Wook Kim*,+, Olivia Walch, and Daniel B. Forger, The combination of topological data analysis and mathematical modeling improves sleep stage prediction from consumer-grade wearables, J. Biol. Rhythms (2024). (link)

• Seokjoo Chae*, Dae Wook Kim, Oleg A. Igoshin, Seunggyu Lee, Jae Kyoung Kim+, Beyond microtubules: The cellular environment at the endoplasmic reticulum attracts proteins to the nucleus, essential for nuclear transport, iScience (2024). (link)

• Dae Wook Kim, Minki P. Lee, and Daniel B. Forger+, Wearable data assimilation to estimate the circadian phase, SIAM J. Applied Math. (2023). (link)

• Dae Wook Kim*,+, Caleb Mayer*, Minki P. Lee, Sung Won Choi, Muneesh Tewari, and Daniel B. Forger, Efficient assessment of real-world dynamics of circadian rhythms in heart rate and body temperature from wearable data, J. R. Soc. Interface (2023). (link) 

• Seokjoo Chae*, Dae Wook Kim, Seunggyu Lee, and Jae Kyoung Kim+, Spatially coordinated collective protein behaviors enable robust signaling from cell membrane to nucleus, iScience (2023). (link)

• Dae Wook Kim*, Ja Min Byun*, Jeong-Ok Lee, Jae Kyoung Kim+ and Youngil Koh+, Chemotherapy delivery time affects anti-lymphoma treatment outcome in a sex-dependent manner, JCI insight (2023). (link) (Media) 

• Yasuko O. Abe*, Hikari Yoshitane+, Dae Wook Kim, Michinori Koebis, Atsu Aiba, Jae Kyoung Kim+, and Yoshitaka Fukada+, Rhythmic transcription of Bmal1 stabilizes the circadian timekeeping system in mammals, Nat. Commun. (2022). (link)

• Dae Wook Kim*, Hyukpyo Hong*, and Jae Kyoung Kim+, Systematic inference identifies a major source of heterogeneity in cell signaling dynamics: the rate-limiting step number, Science Advances (2022). (link) (Media) 

• Miao Lin Pay*, Dae Wook Kim*, David E. Somers, Jae Kyoung Kim+, and Mathias Foo+, Modeling of plant circadian clock for characterizing hypocotyl growth under different light quality conditions, in silico Plants (2022). (link)

• Stephen Beesley*, Dae Wook Kim*, Matthew D’Alessandro, Yuanhu Jin, Kwangjun Lee, Hyunjeong Joo, Yang Young, Robert J. Tomko Jr, John Faulkner, Joshua Gamsby, Jae Kyoung Kim+, and Choogon Lee+, Wake-sleep cycles are severely disrupted by diseases affecting cytoplasmic homeostasis, PNAS (2020). (link) (Media)

This work has been selected as a research highlight in a sister journal to Science, Science Translational Medicine (link), and a Nature Research journal, Communications Biology (link).

• Dae Wook Kim*, Eder Zavala+, and Jae Kyoung Kim+, Wearable technology and systems modeling for personalized chronotherapy, Curr. Opin. Syst. Biol. (2020). (link)

• Xianlin Zou*, Dae Wook Kim, Tetsuya Gotoh, Jingjing Liu, Jae Kyoung Kim, and Carla V. Finkielstein+, A systems biology approach identifies hidden regulatory connections between the circadian and cell-cycle checkpoints, Front. Physiol. (2020). (link)  

• Dae Wook Kim*, Cheng Chang+, Xian Chen, Angela C. Doran, Francois Gaudreadult, Travis Wager, George J. DeMarco, and Jae Kyoung Kim+, Systems approach reveals photosensitivity and PER2 level as determinants of clock-modulator efficacy, Mol. Syst. Biol. (2019; Cover article). (link) (Media)

In Preparation

• Ruby Kim*, Yu Fang, Minki P. Lee, Dae Wook Kim, Zhengxu Tang, Srijan Sen, Daniel B. Forger+, Seasonality explains interindividual differences in shiftwork adaptation, Under Review at npj Digital Medicine.

• Sanghyeok Park*, Dae Wook Kim*, Hyun Kim, Joonho Byun, Sangjoon Chong, Sang Woo Song, Young-Hoon Kim, Young Hyun Cho, Seok Ho Hong, Chang-Ki Hong, Jeong Hoon Kim, Seungjoo Lee+, Jae Kyoung Kim+, Ji Min Lee+, The timing of surgical tumor resection affects survival outcomes in patients with glioblastoma, Submitted.

• Song-Yi Jeong*, Dae Wook Kim*, Seokmin Ha*, Gyeongik Ahn, Gyeong-Im Shin, Cam Chau Nguyen, Joon-Yung Cha, Jae Kyoung Kim+, and Woe-Yeon Kim+, Unraveling strong circadian rhythms: synergy in protein degradation and synthesis, In preparation.

• Dae Wook Kim*, and Daniel B. Forger+, Statistical Tests to determine if a human rhythm is circadian, In preparation.

• Dae Wook Kim*, Caleb Mayer*, Christopher Flora, Sung Won Choi, Muneesh Tewari, and Daniel B. Forger+, Unsupervised real-time personalized detection of febrile events in wearable data using a Kalman filter and an autoencoder, In preparation.

Grant support

• 2025-2030: Outstanding Early-Career Researcher Program,  National Research Foundation of Korea (RS-2025-00561696) "Investigation of core mechanisms in brain dysfunctions through the development of theory for nonlinear filtering and complex systems modeling"

• 2025-2025: Industry-funded project, NP Inc. (G01250053) "Development of a personalized meditation app using emotional and physiological data on XR HMDs"

• 2024-2024: Sogang University G-LAMP, National Research Foundation of Korea (RS-2024-00441954) "Development of a next-generation immuno-oncology drug development platform based on AI and mathematical modeling"

• 2017-2021: Global Ph.D. Fellowship, National Research Foundation of Korea (2017H1A2A1046381) "Development of a mathematical model of human circadian rhythms for drug discovery"

Honors and Awards

• 2023 SMB Poster Prize, Society for Mathematical Biology

• 2022 S-OIL Dissertation Excellence Award (grand prize), S-OIL and Korea Academy of Science and Technology

• 2022 KMS Dissertation Excellence Award, Korean Mathematics Society

• 2021 KSIAM Young Researcher Award, Korean Society for Industrial and Applied Mathematics

• 2020 SRBR Merit Award, Society for Research on Biological Rhythms 

• 2019 SMB Landahl Travel Grant, Society for Mathematical Biology 

• 2017–2022 Global Ph.D. Fellowship, National Research of Foundation of Korea 

• 2012–2016 The National Scholarship for Science and Engineering, Korea Student Aid Foundation 

Talks

• 2025 Computational Neuroscience Winter School, Invited talk, KAIST, Daejeon, Korea

• 2024 Annual Meeting of Korean Society for Industrial and Applied Mathematics, Special Session, Bexco, Busan, Korea

• 2024 KAIST BCS X AKN X K-bioX Brain and Cognitive Sciences Colloquium, Virtual

• 2024 Annual Meeting of Korean Mathematical Society, Special Event Talk, Sungkyunkwan University, Suwon, Korea

• 2024 Annual Meeting of Korean Mathematical Society, Special Session, Sungkyunkwan University, Suwon, Korea

• 2024 Mathematical Sciences Colloquium, KAIST, Daejeon, Korea

• 2024 Brain and Cognitive Sciences Colloquium, KAIST, Daejeon, Korea

• 2024 Applied Mathematics Seminar, Pusan National University, Busan, Korea

• 2024 Annual Meeting of Society for Mathematical Biology, Minisymposium, Konkuk University, Seoul, Korea

• 2024 Mathematics Colloquium, Sogang University, Seoul, Korea

• 2024 Life Science Colloquium, Sogang University, Seoul, Korea

• 2024 Spring Meeting of Korean Society for Industrial and Applied Mathematics, Panel discussion, Kyungpook National University, Daegu, Korea

• 2024 Spring Meeting of Korean Mathematical Society, Invited lecture, KAIST, Daejeon, Korea

• 2023 SIAM NNP Annual Meeting,  Minisymposium, Newark, USA

• 2023 ICIAM Satellite Workshop: Stochastic Modeling and Data Analysis for Biological Systems, IBS, Daejeon, Korea

• 2023 Annual meeting of Society for Mathematical Biology, Poster, The Ohio State University, Columbus, USA 

• 2023 Seminar for KAIST Math Graduate Students, KAIST, Daejeon, Korea

• 2023 IBS Applied Mathematics Seminar, IBS, Daejeon, Korea

• 2023 Applied Mathematics Seminar, Chungbuk National University, Cheongju, Korea

• 2023 Applied Mathematics Colloquium, Pusan National University, Busan, Korea

• 2023 POSTECH MINDS Colloquium, POSTECH, Pohang, Korea

• 2023 Spring Meeting of Korean Mathematical Society, Special Session, Daejeon, Korea

• 2023 Mathematical Biology Seminar, University of Iowa, Invited talk, Virtual

• 2022 Mini-workshop on Recent Trends in Pure and Applied Mathematics, Daejeon, Korea

• 2022 Cognitive Fatigue MURI Research Forum, University of Michigan Ann Arbor, Ann Arbor, USA 

• 2022 SIAM Conference on the Life Sciences, Minisymposium, Pittsburgh, USA 

• 2022 Meeting of Society for Research on Biological Rhythms, Contributed talk, Fernandina Beach, USA

• 2022 SIAM Student Minisymposium in Applied Mathematics, University of Michigan Ann Arbor, Ann Arbor, USA

• 2021 IBS Applied Mathematics Seminar, IBS, Daejeon, Korea

• 2021 NIMS Applied Mathematics Seminar, NIMS, Daejeon, Korea 

• 2021 Applied Mathematics Colloquium, University of Cincinnati, Cincinnati, USA

• 2021 Capsule Research Talks, University of Michigan Ann Arbor, Minisymposium, Virtual 

• 2021 Spring Meeting of Korean Society for Industrial and Applied Mathematics, Young Researcher Award talk, Gangneung-si, Korea

• 2021 Annual Meeting of Society for Mathematical Biology, Minisymposium, virtual

• 2021 BRIC Webinar, Virtual 

• 2020 Annual Meeting of Korean Mathematical Society, Minisymposium, Virtual 

• 2019 Annual Meeting of Society for Mathematical Biology, Minisymposium, Montreal, Canada 

• 2019 A3 Workshop on Mathematical Biology, Contributed talk, Beijing, China 

• 2019 Spring Meeting of Korean Society for Industrial and Applied Mathematics, Special Session, Seoul, Korea 

• 2018 Annual Meeting of Society for Mathematical Biology, Minisymposium, Sydney, Australia 

• 2018 Annual Conference of Korean Society for Mathematical Biology, Special Session, Busan, Korea

• 2018 Spring Meeting of Korean Society for Industrial and Applied Mathematics, Contributed talk, Daejeon, Korea  

Posters

• 2022 Meeting of Society for Research on Biological Rhythms, Fernandina Beach, USA

• 2020 Annual Conference of Korean Society for Industrial and Applied Mathematics, Virtual 

• 2020 Meeting of Society for Research on Biological Rhythms, Virtual 

• 2018 Meeting of Society for Research on Biological Rhythms, Fernandina Beach, USA 

• 2018 International Workshop on Mathematical Biology, Sebu, Philippines 

• 2017 Annual Conference of Korean Society of Sleep Medicine, Seoul, Korea 

• 2017 Annual Conference of Korean Society for Industrial and Applied Mathematics, Busan, Korea 

• 2017 Innovative Statistics and Machine Learning for Precision Medicine, Minneapolis, USA

• 2017 Annual Conference of Korean Society for Mathematical Biology, Jeju, Korea 

• 2017 Spring Meeting of Korean Society for Industrial and Applied Mathematics, Seoul, Korea 

• 2017 A3-NIMS Joint Workshop on Mathematical Biology, Short talk, Daejeon, Korea